DynDom

DynDom - Protein Domain Motion Analysis
Technology No. i491

DynDom is a fully automated program offering the determination of protein domains, hinge axes and amino acid residues that are involved in hinge bending.

The field of protein dynamics is concerned with the conformational changes that occur within proteins. Proteins, such as enzymes, adopt different conformations at different stages of the catalytic cycle, and understanding how proteins make transitions between conformations is an important part of understanding how they work. DynDom is a fully automated program offering the determination of protein domains, hinge axes and amino acid residues that are involved in hinge bending.

Advantages

fully automated

determination of protein domains, hinge axes and hinge bends

easily understandable view of conformational changes.

You can use DynDom if you have two conformations of the same protein, these may be two X-ray structures, or structures generated using simulation techniques, such as molecular dynamics or normal mode analysis. DynDom offers an easily understandable view of the conformational changes that take place. This change may be a complicated one but DynDom aids in visualising the movement of domains as quasi-rigid bodies.

Publications

Proteins 1997, 27(3), 425-437. doi:10.1002/(SICI)1097-0134(199703)27:3<425::AID-PROT10>3.0.CO;2-N

Principal Investigator

Team led by Dr Steven Hayward

Further Details

For more information on this licensing opportunity, please visit contact the IP Office

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Non-Commercial - DynDom - Protein Domain Motion Analysis
DynDom - Protein Domain Motion Analysis

Term: perpetual

Price per licence:
£0.00 excl. VAT

Commercial licence (single user) - HaptiMol
Licence for use of software by commercial organisations

Term: 1 year

Price per user:
TBD